EZM0414 TFA ( —— )

产品货号. M34899 CAS No. 2411759-92-5

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

EZM0414 TFA
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

EZM0414 TFA 是一种有效、选择性和具有口服活性的人类组蛋白甲基转移酶 SETD2 抑制剂。EZM0414 TFA 具有抗增殖作用。
产品描述

EZM0414 TFA is a potent, selective and orally active inhibitor of SETD2 which is a human histone methyltransferase. EZM0414 TFA has anti-proliferative effects.
体外实验

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体内实验

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同义词

——
通路

Others
靶点

Other Targets
受体

Histone Methyltransferase
研究领域

——
适应症

——

CAS Number

2411759-92-5
分子量

514.51
分子式

C24H30F4N4O4
纯度

>98% (HPLC)
溶解度

In Vitro:?DMSO 中的溶解度 : 200 mg/mL (388.72 mM; 超声助溶 ) H2O 中的溶解度 : 6.67 mg/mL (12.96 mM; 超声助溶 (<60°C))
SMILES

OC(=O)C(F)(F)F.CC(=O)N1CCN(CC1)[C@H]1CCC[C@H](C1)NC(=O)c1cc2c(F)ccc(C)c2[nH]1
化学全称

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1. John Lampe, et al. Substituted indoles and methods of use thereof. WO2020037079A1.

计算器

产品手册

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